protein

FSH beta Protein, Human (HEK293, His)

HY-P70238

10 μg;50 μg

160;450 USD

FSH beta Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

160;450 USD

The FSH beta protein and the alpha chain CGA form follicle-stimulating hormone, which gives the hormone heterodimer biological specificity. It binds to FSHR on target cells and initiates downstream signaling, which is critical for follicle development and spermatogenesis. FSH beta Protein, Human (HEK293, His) is the recombinant human-derived FSH beta protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FSH beta Protein, Human (HEK293, His) is 111 a.a., with molecular weight of ~21.0 kDa.

Human

FSH beta Protein, in conjunction with the alpha chain CGA, forms follitropin, the follicle-stimulating hormone, conferring its biological specificity to the hormone heterodimer. This protein binds to FSHR, a G protein-coupled receptor on target cells, initiating downstream signaling pathways. Follitropin plays a crucial role in follicle development and spermatogenesis in reproductive organs. Structured as a heterodimer, the active follitropin consists of an alpha chain/CGA shared with other hormones and a distinctive beta chain/FSHB. Through its interaction with FSHR, FSH beta Protein contributes to the regulation of reproductive processes, highlighting its significance in the intricate orchestration of fertility and reproductive health.

rHuFollitropin subunit beta/FSHB, His; Follitropin Subunit Beta; Follicle-Stimulating Hormone Beta Subunit; FSH-B; FSH-Beta; Follitropin Beta Chain; FSHB

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.