protein

Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc)

HY-P70223

10 μg;50 μg

90;250 USD

Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc)

proteins

HEK293

10 μg;50 μg

90;250 USD

Lymphocyte antigen 86/LY86 acts synergistically with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and influence cytokine production. It plays a crucial role in promoting the high expression of CD180 on the cell surface, forming an M-shaped tetramer with two CD180-LY86 heterodimers. Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc) is the recombinant human-derived Lymphocyte antigen 86/LY86 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc) is 142 a.a., with molecular weight of 45-55 kDa.

Human

The Lymphocyte antigen 86/LY86 protein emerges as a potential collaborator with CD180 and TLR4, mediating the innate immune response to bacterial lipopolysaccharide (LPS) and influencing cytokine production. Additionally, Lymphocyte antigen 86/LY86 plays a crucial role in facilitating efficient CD180 cell surface expression. The structural arrangement involves the formation of an M-shaped tetramer, comprising two CD180-LY86 heterodimers. These characteristics underscore the multifaceted nature of Lymphocyte antigen 86/LY86 in orchestrating immune responses and cellular interactions. Further exploration is essential to unravel the specific molecular mechanisms through which Lymphocyte antigen 86/LY86 contributes to the intricate dynamics of the innate immune system and its collaboration with CD180 and TLR4 in response to bacterial LPS.

rHuLymphocyte antigen 86/MD-1, Fc; Lymphocyte antigen 86; LY86; MD1; Protein MD-1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.