protein

Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His)

HY-P70206A

5 μg;10 μg;50 μg;100 μg

95;160;500;850 USD

Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

95;160;500;850 USD

The maleylacetoacetate isomerase/GSTZ1 protein is a member of the GST superfamily and detoxifies electrophilic molecules. It converts maleylacetoacetate to fumarylacetoacetate, a key step in phenylalanine/tyrosine degradation. Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) is the recombinant human-derived Maleylacetoacetate isomerase/GSTZ1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) is 215 a.a., with molecular weight of ~25 kDa.

Human

The Maleylacetoacetate isomerase/GSTZ1 protein belongs to the glutathione S-transferase (GSTs) superfamily, encoding multifunctional enzymes that play a crucial role in the detoxification of electrophilic molecules, including carcinogens, mutagens, and therapeutic drugs, through conjugation with glutathione. This enzyme specifically catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, a critical step in the phenylalanine/tyrosine degradation pathway. In mice, deficiency of a similar gene leads to oxidative stress. The gene exhibits several transcript variants that encode multiple protein isoforms. Furthermore, the Maleylacetoacetate isomerase/GSTZ1 protein displays broad expression in the liver (RPKM 23.8), testis (RPKM 10.9), and 24 other tissues.

rHuMaleylacetoacetate isomerase/GSTZ1, His; Maleylacetoacetate Isomerase; MAAI; GSTZ1-1; Glutathione S-Transferase Zeta 1; GSTZ1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl,500 mM arginine, pH 7.4, 5% trehalose,5% mannitol and 0.01% Tween80.

Room temperature in continental US; may vary elsewhere.