protein

SLC44A1 Protein, Human (Sf9, His, MBP, FLAG)

HY-P702042

10 μg;20 μg

685;1100 USD

SLC44A1 Protein, Human (Sf9, His, MBP, FLAG)

proteins

Sf9 insect cells

10 μg;20 μg

685;1100 USD

The SLC44A1 protein acts as a choline/H+ and high-affinity ethanolamine/H+ antiporter and is critical for regulating cellular choline and ethanolamine transport. Its dual function actively redistributes intracellular ethanolamine and balances the CDP-Cho and CDP-Etn arms of the Kennedy pathway. SLC44A1 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC44A1 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC44A1 Protein, Human (Sf9, His, MBP, FLAG) is 656 a.a., .

Human

SLC44A1 protein functions as a choline/H+ antiporter, playing a pivotal role in the regulation of cellular choline transport as documented in various studies. Additionally, it acts as a high-affinity ethanolamine/H+ antiporter, thereby controlling the supply of extracellular ethanolamine for the CDP-Etn pathway. This dual functionality allows SLC44A1 to actively redistribute intracellular ethanolamine, maintaining a balance between the CDP-Cho and CDP-Etn arms of the Kennedy pathway. The involvement of SLC44A1 in these processes is crucial for membrane synthesis and myelin production, highlighting its significance in fundamental cellular functions and suggesting potential implications for membrane homeostasis and neural development.

SLC44A1; Choline transporter-like protein 1; CDw92; Solute carrier family 44 member 1; CD92

Greater than 80% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 50 mM HEPES PH 7.5, 150 mM NaCl, 0.03% (w/v) DDM, 0.003% (w/v) CHS

Shipping with dry ice