protein

ACSS2 Protein, Human

HY-P701922

50 μg;100 μg

625;1000 USD

ACSS2 Protein, Human

proteins

E. coli

50 μg;100 μg

625;1000 USD

The ACSS2 protein plays a key role in catalyzing the synthesis of acetyl-CoA from short-chain fatty acids, with acetate being the preferred substrate. Although acetate is efficiently utilized, ACSS2 can also process propionate, albeit with significantly lower affinity. ACSS2 Protein, Human is the recombinant human-derived ACSS2 protein, expressed by E. coli , with tag free. The total length of ACSS2 Protein, Human is 700 a.a., .

Human

ACSS2 (Acetyl-CoA synthetase 2) is an enzyme that plays a crucial role in cellular metabolism by catalyzing the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate for ACSS2, and it efficiently converts acetate into acetyl-CoA. This enzymatic activity is pivotal for various cellular processes, including energy production, lipid metabolism, and histone acetylation. ACSS2 can also utilize propionate, albeit with a much lower affinity compared to acetate. The ability of ACSS2 to generate acetyl-CoA from short-chain fatty acids contributes to the pool of acetyl-CoA available for diverse metabolic pathways, emphasizing its importance in cellular energy homeostasis and the integration of metabolic signals.

ACSS2; Acetyl-coenzyme A synthetase; cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme; Propionate--CoA ligase

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.22 μm filtered solution of 50 mM HEPES (pH 7.5), 200 mM NaCl, 20% glycerol, 1 mM DTT.

Shipping with dry ice