protein

IGF-I/IGF-1 Protein, Human (70a.a)

HY-P7018

2 μg;5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

30;42;51;93;130;230;330;500 USD

IGF-I/IGF-1 Protein, Human (70a.a)

proteins

E. coli

2 μg;5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

30;42;51;93;130;230;330;500 USD

375588468

IGF-I/IGF-1 Protein, Human (70a.a) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone; IGF-I/IGF-1 Protein also mediates neuroprotective mechanism.

Human

Insulin-like growth factor (IGF) system has been shown to modulate growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. Insulin-like Growth factor-1 (IGF-I) is produced by osteoblasts, and its mitogenic effects are mediated by their binding to the IGF plasma membrane receptors. The IGF type 1 receptor binding to both IGF-I and IGF-II, is thought to be the predominate receptor involved in mediating the effects of these growth factors in most cell types, including osteoblasts [1] . Insulin-like growth factor-1 (IGF-1) is a neurotrophic factor capable of mediating neuroprotective and neuroplasticity mechanisms. Targeted overexpression of IGF-1 enhances the generation of hippocampal newborn neurons in brain-injured mice [2] .

rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4 or 20 mM NaAc-HAc, pH 4.5 or PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.