protein

KRAS Protein, Human (G12S, His)

HY-P70153

5 μg;10 μg;50 μg;100 μg

35;50;150;255 USD

KRAS Protein, Human (G12S, His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

35;50;150;255 USD

KRAS protein is a key Ras family member that binds GDP/GTP and has intrinsic GTPase activity. Its critical role in regulating cell proliferation emphasizes its importance in cellular processes. KRAS Protein, Human (G12S, His) is the recombinant human-derived KRAS, expressed by E. coli , with N-6*His labeled tag. ,

Human

KRAS, a pivotal member of the Ras protein family, exhibits the ability to bind GDP/GTP and possesses intrinsic GTPase activity. Its crucial involvement in the regulation of cell proliferation underscores its significance in cellular processes. Notably, KRAS plays a prominent role in promoting oncogenic events, particularly in colorectal cancer (CRC), where it induces transcriptional silencing of tumor suppressor genes (TSGs) in a ZNF304-dependent manner. This multifaceted functionality highlights KRAS as a key player in cellular dynamics and emphasizes its relevance in both normal and pathological cellular processes.

rHuKRAS-G12S, His; Ki-Ras; c-K-ras; KRAS2; RASK2; CFC2

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 5% trehalose.

Room temperature in continental US; may vary elsewhere.