protein

Ketohexokinase/KHK Protein, Human (HEK293, His)

HY-P70146

10 μg;50 μg

104;314 USD

Ketohexokinase/KHK Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

104;314 USD

Ketohexokinase (KHK) proteins play a key role in carbohydrate metabolism by catalyzing the phosphorylation of ketoglycosides into fructose-1-phosphate. This enzyme activity is a key step in the utilization and processing of fructose within cells. Ketohexokinase/KHK Protein, Human (HEK293, His) is the recombinant human-derived Ketohexokinase/KHK protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Ketohexokinase/KHK Protein, Human (HEK293, His) is 298 a.a., with molecular weight of ~30.0 kDa.

Human

The Ketohexokinase (KHK) protein is a crucial enzyme that catalyzes the phosphorylation of the ketose sugar fructose, converting it to fructose-1-phosphate. This phosphorylation reaction represents a key step in fructose metabolism and is pivotal for regulating various cellular processes. By initiating the conversion of fructose to fructose-1-phosphate, KHK plays a central role in diverting fructose away from glycolysis and towards alternative metabolic pathways. This enzyme is particularly important in the liver, where it contributes to the regulation of fructose metabolism and its potential impact on lipogenesis and triglyceride synthesis. Understanding the functions of KHK provides insights into the molecular mechanisms governing fructose utilization and its implications for metabolic homeostasis.

rHuKetohexokinase/KHK, His; Ketohexokinase; Hepatic fructokinase; KHK

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50nM KCl, 10% Glycerol, pH 7.4.

Shipping with dry ice.