protein

USP25 Protein, Human

HY-P701444

10 μg;50 μg

210;550 USD

USP25 Protein, Human

proteins

E. coli

10 μg;50 μg

210;550 USD

The USP25 protein acts as a deubiquitinating enzyme and plays a key role in the hydrolysis of the ubiquitin moiety conjugated to the substrate. This function enables processing of newly synthesized ubiquitin, recycling of ubiquitin molecules, and editing of polyubiquitin chains, thus preventing proteasomal degradation of substrates. USP25 Protein, Human is the recombinant human-derived USP25 protein, expressed by E. coli , with tag free. The total length of USP25 Protein, Human is 1054 a.a., .

Human

Ubiquitin-specific protease 25 (USP25) is a deubiquitinating enzyme with the capacity to hydrolyze ubiquitin moieties conjugated to substrates, thereby participating in the processing of newly synthesized ubiquitin, recycling ubiquitin molecules, and editing polyubiquitin chains. USP25 plays a crucial role in preventing the proteasomal degradation of substrates by cleaving ubiquitin chains. Notably, it exhibits hydrolytic activity towards both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains, showcasing its versatility in targeting different ubiquitin linkage types. Additionally, a muscle-specific isoform of USP25, known as USP25m, is suggested to play a role in the regulation of muscular differentiation and function, indicating its potential significance in specific cellular contexts.

USP25; Ubiquitin carboxyl-terminal hydrolase 25; Deubiquitinating enzyme 25; USP on chromosome 21; Ubiquitin thioesterase 25; Ubiquitin-specific-processing protease 25

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl, pH7.5, 200 mM NaCl, 20% glycerol.

Shipping with dry ice