protein

Spondin-2/SPON2 Protein, Human (Q9BUD6, HEK293, His)

HY-P70142A

5 μg;10 μg;50 μg

40;60;150 USD

Spondin-2/SPON2 Protein, Human (Q9BUD6, HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

40;60;150 USD

Spondin-2/SPON2 protein, as a cell adhesion molecule, plays a key role in promoting the adhesion and growth of hippocampal embryonic neurons.In addition to its role in neurodevelopment, SPON2 acts as a direct binder of bacteria and their components, functioning as an opsonin to promote phagocytosis of bacteria by macrophages.Spondin-2/SPON2 Protein, Human (Q9BUD6, HEK293, His) is the recombinant human-derived Spondin-2/SPON2 protein, expressed by HEK293 , with His labeled tag.

Human

Spondin-2, also known as SPON2, is a versatile cell adhesion protein crucial for hippocampal embryonic neuron adhesion and outgrowth. Its functional diversity extends to binding bacteria and their components, serving as an opsonin that facilitates macrophage phagocytosis of bacteria. Essential in initiating the innate immune response, SPON2 acts as a unique pattern-recognition molecule in the extracellular matrix (ECM) for microbial pathogens, specifically binding bacterial lipopolysaccharide (LPS). Existing as a monomer, SPON2 interacts with integrins, further emphasizing its role in mediating cell-matrix interactions (

rHuSpondin-2/SPON2, His; Spondin-2; Differentially expressed in cancerous and non-cancerous lung cells 1; DIL-1; Mindin; SPON2

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.