protein

USP48 Protein, Human (Sf9, FLAG)

HY-P701422

20 μg;50 μg

350;790 USD

USP48 Protein, Human (Sf9, FLAG)

proteins

Sf9 insect cells

20 μg;50 μg

350;790 USD

USP48 protein, a deubiquitinase, hydrolyzes ubiquitin bonds at the C-terminal Gly, processing poly-ubiquitin precursors and ubiquitinated proteins. It may regulate NF-kappa-B activation by the TNF receptor superfamily via RELA and TRAF2 interactions. With potential roles at postsynaptic sites, USP48 exhibits multifunctionality, influencing ubiquitin processing and signaling pathways involved in immune response and synaptic function. USP48 Protein, Human (Sf9, FLAG) is the recombinant human-derived USP48 protein, expressed by Sf9 insect cells , with C-Flag labeled tag. The total length of USP48 Protein, Human (Sf9, FLAG) is 1034 a.a., .

Human

The USP48 protein functions as a deubiquitinase, specifically recognizing and hydrolyzing the peptide bond at the C-terminal Gly of ubiquitin. It is implicated in the processing of both poly-ubiquitin precursors and ubiquitinated proteins. Additionally, USP48 may play a role in regulating NF-kappa-B activation by the TNF receptor superfamily through interactions with RELA and TRAF2. Furthermore, it is suggested to have a potential regulatory function at postsynaptic sites. These diverse activities highlight the multifunctional nature of USP48 in cellular processes, encompassing ubiquitin processing and modulation of signaling pathways implicated in immune response and synaptic function.

USP48; Ubiquitin carboxyl-terminal hydrolase 48; Deubiquitinating enzyme 48; Ubiquitin thioesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.22 μm filtered solution of 50 mM HEPES, pH7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.

Shipping with dry ice