protein

CHRDL2 Protein, Mouse (HEK293, His)

HY-P70135

2 μg;10 μg;50 μg;100 μg

35;95;250;440 USD

CHRDL2 Protein, Mouse (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

35;95;250;440 USD

CHRDL2 protein is related to tumor angiogenesis and may negatively regulate BMP activity by hindering the interaction between BMP and receptors. It significantly affects cartilage formation and regeneration, suggesting a role in regulating matrix accumulation of immature mesenchymal cells. CHRDL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CHRDL2 protein, expressed by HEK293 , with C-6*His labeled tag.

Mouse

CHRDL2 Protein is implicated in tumor angiogenesis, potentially acting as a negative regulator of BMPs activity by obstructing their interaction with respective receptors. It exhibits a significant impact on cartilage formation and regeneration, suggesting a role in modulating the rate of matrix accumulation from immature mesenchymal cells. Furthermore, CHRDL2 may play a regulatory role during myoblast and osteoblast differentiation and maturation processes. Notably, CHRDL2 interacts with various members of the BMP family, including GDF5, INHBA, BMP2, BMP4, BMP5, BMP6, and BMP7, indicating its involvement in diverse cellular and developmental pathways.

rMuChordin-like protein 2/CHRDL2, His; Chordin-like protein 2; BNF-1; CHRDL2; chordin-like 2; chordin-like protein 2

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.