protein

vacA Protein, Helicobacter pylori (His)

HY-P701331

5 μg;10 μg;20 μg;50 μg;100 μg

75;115;178;340;545 USD

vacA Protein, Helicobacter pylori (His)

proteins

E. coli

5 μg;10 μg;20 μg;50 μg;100 μg

75;115;178;340;545 USD

The VacA protein takes center stage, demonstrating its unique ability to induce vacuole formation in eukaryotic cells, affecting cell morphology. This process involves the formation of vacuoles, highlighting the role of VacA as a key regulator of cell structure. vacA Protein, Helicobacter pylori (His) is the recombinant vacA protein, expressed by E. coli , with N-6*His labeled tag. The total length of vacA Protein, Helicobacter pylori (His) is 209 a.a., with molecular weight of 26.6 kDa.

Others

VacA protein takes center stage with its distinctive ability to induce vacuolation in eukaryotic cells, showcasing its potent impact on cellular morphology. This process, characterized by the formation of vacuoles within the cells, reflects VacA's role as a key modulator of cellular architecture. Beyond its influence on cell morphology, VacA is implicated in causing ulceration and gastric lesions, underscoring its significant role in the pathogenesis of gastric disorders. The dual effects of vacuolation induction and the promotion of gastric lesions position VacA as a critical virulence factor, shedding light on its role in the complex interplay between bacterial pathogens and host cells in the context of gastric pathology.

Vacuolating cytotoxin autotransporter;

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0 or PBS, pH 7.0, 8% trehalose.

Room temperature in continental US; may vary elsewhere.