protein

T-PA Protein, Mouse (HEK293, His)

HY-P701312

5 μg;10 μg;50 μg

88;150;420 USD

T-PA Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

88;150;420 USD

The T-PA protein converts the inactive plasminogen to active plasmin by hydrolyzing a single Arg-Val bond.This conversion regulates plasmin-mediated proteolysis and is involved in tissue remodeling, degradation, and cell migration.T-PA also contributes to the prevention of polyspermy during oocyte activation by participating in the cortical granule reaction.T-PA Protein, Mouse (HEK293, His) is the recombinant mouse-derived T-PA protein, expressed by HEK293 , with C-His labeled tag.

Mouse

The T-PA protein functions by converting the inactive zymogen plasminogen into active plasmin through the hydrolysis of a single Arg-Val bond. This conversion is crucial for regulating plasmin-mediated proteolysis, which is involved in tissue remodeling, degradation, cell migration, and various physiological and pathological processes. Additionally, during oocyte activation, T-PA plays a role in the cortical granule reaction within the zona reaction, contributing to the prevention of polyspermy.

Tissue-type plasminogen activator; t-PA; Plat

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.