FGF-23 Protein, Human | MedChem Express LLC HY-P7013 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

FGF-23 Protein, Human

catalog :

HY-P7013

quantity :

10 μg;50 μg

price :

140;440 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7013

Product Name :

FGF-23 Protein, Human

Product Type :

proteins

Host Species :

E. coli

Size :

10 μg;50 μg

List Price :

140;440 USD

list of Pubmed id :

375588461

Product Description :

FGF-23 Protein, Human is a unique FGF subfamily member, acts as a hormone and requires α-Klotho to signal through canonical FGFR, and induces hypertrophy and mineralization during chondrogenesis.

SpeciesSummary :

Human

Background :

Recombinant Human Fibroblast Growth Factor 23 is a unique FGF subfamily member, acts as a a hormone and requires a cofactor to signal through canonical FGFR, and induces hypertrophy and mineralization during chondrogenesis [1] . FGF23 is a secreted, circulating protein of 32 kDa that is predominantly produced by osteocytesin bone and functions in distant target organs in an endocrine fashion. FGF23 generally requires an FGF receptor (FGFR) and α-Klotho to evoke its signaling. GF23 binds to an FGFR-α-Klotho complex and induces the phosphorylation of FGFR and the expression of early growth response-1 (Egr-1), which encodes a transcription factor [2] .

ALTnames :

rHuFGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS, pH 7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage