protein

FITC-Labeled CEACAM5 Protein, Human (HEK293, His, Avi)

HY-P701271

20 μg;50 μg;100 μg

315;600;960 USD

FITC-Labeled CEACAM5 Protein, Human (HEK293, His, Avi)

proteins

HEK293

20 μg;50 μg;100 μg

315;600;960 USD

CEACAM5 protein is a cell surface glycoprotein that cooperates with carcinoembryonic antigen-related molecules (such as CEACAM6) to participate in cell adhesion, intracellular signaling, and tumor progression. FITC-Labeled CEACAM5 Protein, Human (HEK293, His, Avi) is the recombinant human-derived FITC-Labeled CEACAM5 protein, expressed by HEK293 , with His and Avi labeled tag.

Human

CEACAM5 protein, a cell surface glycoprotein, assumes a multifaceted role in cell adhesion, intracellular signaling, and tumor progression. Functioning as a mediator of both homophilic and heterophilic cell adhesion, CEACAM5 interacts with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. In the context of tumor progression, CEACAM5 acts as an oncogene, promoting tumor advancement and inducing resistance to anoikis in colorectal carcinoma cells. Additionally, during microbial infection, CEACAM5 serves as a receptor for E. coli Dr adhesins, and the binding of these adhesins results in the dissociation of the CEACAM5 homodimer. These diverse functions underscore the versatility of CEACAM5 in regulating cellular processes and highlight its significance in both physiological and pathological contexts.

CEACAM-5; CD66e; CEA; Meconium antigen 100

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from 0.22 μm filtered solution of PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.