protein

RPRD1B Protein, Human (HEK293, N-His)

HY-P701252

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

52;88;247;420;1170;1980 USD

RPRD1B Protein, Human (HEK293, N-His)

Protein

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

52;88;247;420;1170;1980 USD

RPRD1B, is a necessary scaffolding protein that maintains genetic integrity by regulating resolution of R-loops at both the transcription termination and DNA double-strand break (DSB) repair levels. In endometrial cancers, RPRD1B accelerates cell cycle through up-regulating Cyclin D1, CDK4, and CDK6. In addition, RPRD1B enhancse transcription of CCND1 and promotes cell proliferation by interacting with RNA polymerase II. RPRD1B enhances the β-Catenin·TCF4 transcriptional activity in response to Wnt signaling. RPRD1B Protein, Human (HEK293, N-His) is the recombinant human-derived RPRD1B protein, expressed by HEK293 , with N-6*His labeled tag.