protein

LacI WT Protein, E.coli (His)

HY-P701244

5 μg;10 μg;50 μg

109;186;520 USD

LacI WT Protein, E.coli (His)

proteins

E. coli

5 μg;10 μg;50 μg

109;186;520 USD

LacI, the lactose operon repressor, regulates lactose metabolism by binding to the operator region and repressing gene transcription. The presence of the inducer, allolactose, alters its binding affinity, derepressing the operon. As a homotetramer, LacI finely tunes lactose metabolism, orchestrating regulatory mechanisms in response to the cellular environment. LacI WT Protein, E.coli (His) is the recombinant E. coli-derived LacI WT protein, expressed by E. coli , with N-10*His labeled tag. The total length of LacI WT Protein, E.coli (His) is 360 a.a., with molecular weight of approximately 42 kDa.

E.coli

LacI, the repressor of the lactose operon, plays a crucial role in the regulation of lactose metabolism. It functions by binding to the operator region and repressing the transcription of genes involved in lactose utilization. The binding affinity is altered in the presence of the inducer, allolactose, which leads to the derepression of the operon. As a homotetramer, LacI orchestrates the regulatory mechanisms that finely tune lactose metabolism in response to the cellular environment.

rE.coLactose operon repressor/LacI, His; Lactose operon repressor; LacI

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm sterile filtered 50 mM Tris-HCL, 300 mM NaCL, pH 8.0.

Room temperature in continental US; may vary elsewhere.