protein

NFKBIE/IKB epsilon Protein, Human (His)

HY-P701230

5 μg;10 μg;50 μg

53;89;250 USD

NFKBIE/IKB epsilon Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg

53;89;250 USD

NFKBIE/IKB epsilon Protein crucially inhibits NF-kappa-B by forming a cytoplasmic complex, preventing its DNA-binding activity. It targets specific complexes involving p50-p65, p50-c-Rel, and interacts with subunits RELA, REL, NFKB1 (p50), and NFKB2 (p52). NFKBIE/IKB epsilon plays a pivotal role in regulating NF-kappa-B signaling, controlling nuclear translocation and transcriptional activities. NFKBIE/IKB epsilon Protein, Human (His) is the recombinant human-derived NFKBIE/IKB epsilon protein, expressed by E. coli , with N-10*His labeled tag. The total length of NFKBIE/IKB epsilon Protein, Human (His) is 500 a.a., with molecular weight of ~57 kDa.

Human

NFKBIE/IKB epsilon protein plays a crucial role in inhibiting NF-kappa-B by forming a complex with it, thereby sequestering it in the cytoplasm. It exerts its inhibitory effects by preventing the DNA-binding activity of NF-kappa-B, specifically targeting complexes involving p50-p65, p50-c-Rel, and interacting with individual subunits such as RELA, REL, NFKB1 (p50), and NFKB2 (p52). Through these interactions, NFKBIE/IKB epsilon contributes to the regulation of NF-kappa-B signaling, playing a pivotal role in controlling its nuclear translocation and subsequent transcriptional activities.

C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1; RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from sterile 50 mM Tris-HCL, 200 mM NaCl, 200 mM arginine, pH 8.0, 10% Glycerol.

Room temperature in continental US; may vary elsewhere.