protein

PPM1H protein, Human (HEK293, His)

HY-P701180

5 μg;10 μg;50 μg

75;125;350 USD

PPM1H protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

75;125;350 USD

PPM1H, the enzyme subject, dephosphorylates CDKN1B at 'Thr-187,' critically regulating cellular processes. By preventing proteasomal degradation, PPM1H stabilizes CDKN1B, emphasizing its role in protein stabilization. This dephosphorylation event, orchestrated by PPM1H, intricately controls CDKN1B levels, showcasing its involvement in modulating cell cycle progression and regulating key cellular functions. PPM1H, Human (HEK293, His) is the recombinant human-derived PPM1H, expressed by HEK293 , with C-His labeled tag. The total length of PPM1H, Human (HEK293, His) is 514 a.a., with molecular weight of ~75 kDa.

Human

The subject, PPM1H, functions as an enzyme that dephosphorylates CDKN1B at 'Thr-187,' thereby playing a critical role in the regulation of cellular processes. By removing the phosphorylation signal at this specific site, PPM1H prevents the proteasomal degradation of CDKN1B, emphasizing its role in stabilizing the protein. This dephosphorylation event orchestrated by PPM1H contributes to the intricate control of CDKN1B levels, highlighting the enzyme's involvement in the modulation of cell cycle progression and the regulation of key cellular functions.

Protein phosphatase 1H, PPM1H

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of 25 mM Tris-HCl, 150 mM NaCl, pH 7.4, 10% Glycerol.

Room temperature in continental US; may vary elsewhere.