protein

EDAR Protein, Mouse (HEK293, Fc)

HY-P70115

10 μg;50 μg

104;314 USD

EDAR Protein, Mouse (HEK293, Fc)

proteins

HEK293

10 μg;50 μg

104;314 USD

EDAR protein is a receptor for the EDA isoform TAA, which, unlike TA-2, may activate the NF-kappa-B and JNK pathways, indicating its involvement in immune signaling. In addition, EDAR may cause caspase-independent cell death. EDAR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EDAR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EDAR Protein, Mouse (HEK293, Fc) is 163 a.a., with molecular weight of 58-74 kDa.

Mouse

EDAR Protein functions as a receptor specifically for EDA isoform TAA, distinguishing it from isoform TA-2. This receptor potentially mediates the activation of NF-kappa-B and JNK pathways, suggesting its involvement in signaling cascades associated with immune responses. Additionally, EDAR may play a role in promoting caspase-independent cell death. Its binding to EDARADD and association with key proteins such as TRAF1, TRAF2, TRAF3, and NIK underscore its role in complex signaling networks, emphasizing its significance in cellular processes beyond immune modulation, potentially contributing to cellular survival and programmed cell death mechanisms.

rMuTumor necrosis factor receptor superfamily member EDAR/EDAR, Fc; Tumor necrosis factor receptor superfamily member EDAR; Anhidrotic ectodysplasin receptor 1; Downless; Ectodermal dysplasia receptor; Ectodysplasin-A receptor

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.