protein

TREML1 Protein, Human (147a.a, HEK293, hFc)

HY-P701054

20 μg;50 μg;100 μg

185;350;560 USD

TREML1 Protein, Human (147a.a, HEK293, hFc)

proteins

HEK293

20 μg;50 μg;100 μg

185;350;560 USD

TREML1 is a trigger receptor 1 expressed on myeloid cells that activates myeloid cells via the adaptor protein DAP12. TREML1 promotes microglial phagocytosis of Aβ and is associated with the immune response to AD. TREML1 Protein, Human (147a.a, HEK293, hFc) is the recombinant human-derived TREML1 protein, expressed by HEK293 , with C-hFc labeled tag.

Human

TREML1 is a trigger receptor 1 expressed on myeloid cells, and monocytes/macrophages and blood neutrophils are the main effector cells in the innate response to human TREML1. TREML1 activates myeloid cells through the adaptor protein DAP12. TREMs family not only participate in the regulation of microglial phagocytosis and amyloid clearance but also play an indispensable role in the neuroinflammatory response of AD. TREML1 promotes microglial phagocytosis of Aβ and is associated with the immune response to AD [1] [2] [3] .

TLT-1; TREML1; TLT1; Trem-like transcript 1; UNQ1825/PRO3438; dJ238O23.3; GLTL1825; MGC119173; PRO3438

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 8% Trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.