protein

TPBG/5T4 Protein, Human (HEK293, hFc)

HY-P701049

20 μg;50 μg;100 μg

160;300;490 USD

TPBG/5T4 Protein, Human (HEK293, hFc)

proteins

HEK293

20 μg;50 μg;100 μg

160;300;490 USD

TPBG/5T4 protein acts as an inhibitor of Wnt/β-catenin signaling, possibly by interacting indirectly with LRP6 and hindering Wnt3a-dependent LRP6 internalization. This means that TPBG/5T4 plays a crucial role in regulating the complex Wnt/β-catenin signaling pathway and exerts a regulatory influence on cellular responses related to this pathway. TPBG/5T4 Protein, Human (HEK293, hFc) is the recombinant human-derived TPBG/5T4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TPBG/5T4 Protein, Human (HEK293, hFc) is 324 a.a., with molecular weight of 75-105 kDa.

Human

The TPBG/5T4 protein appears to serve as an inhibitor of Wnt/beta-catenin signaling, potentially achieved through indirect interaction with LRP6, thereby impeding Wnt3a-dependent LRP6 internalization. This implies a crucial role for TPBG/5T4 in modulating the intricate Wnt/beta-catenin signaling pathway, exerting regulatory influence on cellular responses associated with this pathway. Further exploration of the specific molecular mechanisms governing the interaction between TPBG/5T4 and LRP6, as well as its impact on Wnt3a-dependent LRP6 internalization, could yield valuable insights into the functional significance of TPBG/5T4 in shaping Wnt/beta-catenin signaling dynamics and its potential implications for various cellular processes.

M6P1; 5T4AG; WAIF1; TPBG; 5T4

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.