protein

Dermatopontin/DPT Protein, Mouse (HEK293, Fc)

HY-P70104

10 μg;50 μg

100;300 USD

Dermatopontin/DPT Protein, Mouse (HEK293, Fc)

proteins

HEK293

10 μg;50 μg

100;300 USD

The dermapontin (DPT) protein mediates adhesion by binding to integrins on the cell surface and serves as a communication link between dermal fibroblasts and the extracellular matrix. It enhances TGFB1 activity, inhibits cell proliferation, accelerates collagen fiber formation, and stabilizes its resistance to low-temperature dissociation. Dermatopontin/DPT Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Dermatopontin/DPT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Dermatopontin/DPT Protein, Mouse (HEK293, Fc) is 183 a.a., with molecular weight of ~55 kDa.

Mouse

Dermatopontin (DPT) protein functions as a mediator of adhesion through binding to cell surface integrins and acts as a potential communication link between dermal fibroblast cell surfaces and the extracellular matrix. Additionally, DPT enhances the activity of TGFB1, inhibits cell proliferation, and plays a role in accelerating collagen fibril formation while stabilizing collagen fibrils against low-temperature dissociation. Its interactions with TGFB1, DCN, and collagen underscore its involvement in the modulation of cellular adhesion and extracellular matrix dynamics.

rMuDermatopontin, Fc; Early quiescence protein 1; EQ-1; Tyrosine-rich acidic matrix protein; TRAMP

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.