product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
LRRC15 Protein, Canine (HEK293, His)
catalog :
HY-P701020
quantity :
20 μg;50 μg;100 μg
price :
245;470;750 USD
more info or order :
product information
Catalog Number :
HY-P701020
Product Name :
LRRC15 Protein, Canine (HEK293, His)
Product Type :
proteins
Host Species :
HEK293
Size :
20 μg;50 μg;100 μg
List Price :
245;470;750 USD
Product Description :
LRRC15 protein actively modulates SARS-CoV-2 infectivity by directly interacting with the spike protein, inhibiting ACE2(+) cell infection. While not an entry receptor, LRRC15, expressed on nearby cells, sequesters virions, and its direct interaction with the spike protein's RBD domain leads to virion sequestration at the cell surface. LRRC15 Protein, Canine (HEK293, His) is the recombinant canine-derived LRRC15 protein, expressed by HEK293 , with C-His labeled tag. The total length of LRRC15 Protein, Canine (HEK293, His) is 519 a.a., with molecular weight of 70-80 kDa.
SpeciesSummary :
Canine
Background :
The LRRC15 protein modulates the infectivity of SARS-CoV-2 by interacting with its spike protein. It does not function as an entry receptor for SARS-CoV-2, but instead, when expressed on nearby cells, it sequesters virions and inhibits SARS-CoV-2 infection of ACE2(+) cells in a trans manner. Furthermore, LRRC15 protein directly interacts with the RBD domain of the human coronavirus SARS-CoV-2 spike protein, leading to virion sequestration at the cell surface.
ALTnames :
LIB; LRRC15
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage :
Room temperature in continental US; may vary elsewhere.
more info or order :
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com609-228-6898
headquarters: USA