protein

Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi)

HY-P701015

20 μg;50 μg;100 μg

307;676;1150 USD

Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi)

proteins

HEK293

20 μg;50 μg;100 μg

307;676;1150 USD

Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi), has molecular weight of 90-130 kDa.

Mouse

Integrin alpha-V/beta-3 (ITGAV:ITGB3) acts as a receptor for CD40LG and binds to the Lilrb4a/Gp49b receptor, enhancing its inhibitory effect on mast cell activation. ITGAV:ITGB3 also suppresses marginal zone B cell antibody production through interaction with Lilrb4a. It forms a heterodimer with ITGAV and interacts with various ligands, including RAB25, CIB1, FBLN5, CCN3, ADGRA2, FGF2, CX3CR1, CX3CL1, NRG1, ERBB3, FGF1, FGFR1, IGF1, IGF1R, IGF2, and PTN. It also forms a complex with PTPRZ1 and PTN to stimulate endothelial cell migration.

αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV Integrin alpha V β 3; β3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.