product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
IL-27R alpha/TCCR Protein, Human (HEK293, His)
catalog :
HY-P701013
quantity :
20 μg;50 μg
price :
110;240 USD
more info or order :
product information
Catalog Number :
HY-P701013
Product Name :
IL-27R alpha/TCCR Protein, Human (HEK293, His)
Product Type :
proteins
Host Species :
HEK293
Size :
20 μg;50 μg
List Price :
110;240 USD
Product Description :
IL-27R α/TCCR protein, as a receptor for IL27, relies on IL6ST/GP130 for signal transduction and activates STAT3 and STAT1. It is also part of the IL6ST/GP130 and CNTFR complex, acting as a receptor for the neuroprotective peptide human peptide. IL-27R alpha/TCCR Protein, Human (HEK293, His) is the recombinant human-derived IL-27R alpha/TCCR protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-27R alpha/TCCR Protein, Human (HEK293, His) is 483 a.a., with molecular weight of 75-105 kDa.
SpeciesSummary :
Human
Background :
IL-27R alpha/TCCR, a receptor for IL27, relies on IL6ST/GP130 to facilitate signal transduction in response to IL27, operating through STAT3 and STAT1 pathways. This receptor is also implicated in the recognition of the neuroprotective peptide humanin, forming a complex with IL6ST/GP130 and CNTFR. Beyond its involvement in the regulation of Th1-type immune responses, IL-27R alpha/TCCR is associated with innate defense mechanisms. It forms part of a receptor complex comprising IL6ST/GP130, IL27RA/WSX1, and CNTFR, and this complex interacts with the neuroprotective peptide humanin.
ALTnames :
IL-27RA; TCCR; IL27RA; IL-27R-alpha; IL27R alpha; WSX-1; WSX1; ZcytoR1; CRL1; IL-27 RA; IL27 RA
Purity :
Greater than 90% as determined by reducing SDS-PAGE.
Buffer :
Supplied as a 0.22μm filtered solution of PBS, pH 7.4.
Storage :
Shipping with dry ice
more info or order :
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com609-228-6898
headquarters: USA