protein

PF-4/CXCL4 Protein, Human (Biotinylated, His-Avi)

HY-P700981

20 μg;50 μg;100 μg

320;700;1190 USD

PF-4/CXCL4 Protein, Human (Biotinylated, His-Avi)

proteins

E. coli

20 μg;50 μg;100 μg

320;700;1190 USD

Wnt-10b protein is a signaling molecule that plays a key role in embryonic development and tissue homeostasis. It is involved in regulating cell proliferation, differentiation and migration. PF-4/CXCL4 Protein, Human (Biotinylated, His-Avi) is the recombinant human-derived PF-4/CXCL4 protein, expressed by E. coli , with C-Avi, N-His labeled tag. The total length of PF-4/CXCL4 Protein, Human (Biotinylated, His-Avi) is 70 a.a., with molecular weight of 13 kDa.

Human

The PF-4/CXCL4 Protein, a member of the CXC chemokine family, is encoded by this gene. Released from the alpha granules of activated platelets in the form of a homotetramer, this chemokine exhibits high affinity for heparin and plays a crucial role in platelet aggregation. Beyond its involvement in platelet function, PF-4/CXCL4 is chemotactic for various cell types and serves as an inhibitor of hematopoiesis, angiogenesis, and T-cell function. Additionally, it demonstrates antimicrobial activity against Plasmodium falciparum. The gene displays biased expression, with elevated levels in the bone marrow (RPKM 14.3), spleen (RPKM 2.7), and one other tissue, underscoring its potential significance in various physiological contexts across multiple organs.

PF-4; Oncostatin-A; CXCL4; SCYB4; Iroplact; MGC138298

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in 4mM HCl, pH 3.0. Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.