protein

C1s/Complement component C1s Protein, Human (HEK293, His)

HY-P700696

20 μg;50 μg

182;400 USD

C1s/Complement component C1s Protein, Human (HEK293, His)

proteins

HEK293

20 μg;50 μg

182;400 USD

C1s/Complement component C1s, a serine protease and B chain, forms C1 with C1q and C1r, initiating the classical complement pathway. Activated by C1r, C1s then activates downstream components C2 and C4, crucially driving the complement system cascade. C1s/Complement component C1s Protein, Human (HEK293, His) is the recombinant human-derived C1s/Complement component C1s protein, expressed by HEK293 , with C-His labeled tag. The total length of C1s/Complement component C1s Protein, Human (HEK293, His) is 673 a.a., with molecular weight of 55-60 kDa (light chain), 32-35 kDa (heavy chain).

Human

C1s, a serine protease, constitutes the B chain that, in conjunction with C1q and C1r, assembles to create C1, the initial component in the classical pathway of the complement system. Activation of C1s is facilitated by C1r, enabling it to subsequently activate downstream components C2 and C4, thereby initiating the cascade of events essential for complement system function.

Complement C1s subcomponent; C1 esterase;

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.