protein

Collectin-11/CL-K1 Protein, Mouse (HEK293, His)

HY-P70067

10 μg;50 μg

115;345 USD

Collectin-11/CL-K1 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg

115;345 USD

Collectin-11/CL-K1 Protein is a secreted protein that activates tyrosine kinase receptors (EGFR, HER3) and ERK , JNK , and AKT signaling pathways to promote cell proliferation. Collectin-11/CL-K1 Protein plays an important role in innate immunity and apoptosis . Collectin-11/CL-K1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Collectin-11/CL-K1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collectin-11/CL-K1 Protein, Mouse (HEK293, His) is 246 a.a., with molecular weight of 30-35 kDa.

Mouse

Collectin-11 is a secreted protein that plays an important role in innate immunity by binding to carbohydrate antigens on microorganisms and activating complement by recruiting mannose-binding lectins (MBL) associated serine proteases (MASPs). Collectin-11 can activate tyrosine kinase receptors (EGFR, HER3) and ERK , JNK and AKT signaling pathways, which can directly stimulate the proliferation of mouse melanoma cells. Collectin-11 plays a role in apoptosis by binding to DNA on the surface of apoptotic cells in a calcium-independent manner and activating complement in response to this binding. Collectin-11 plays a protective role in urinary tract infections (UTI) induced by uropathogenic Escherichia coli (UPEC) by inducing innate immune defense [1] [2] [3] [4] [5] .

rMuCollectin-11, His ; Collectin-11; Collectin Kidney Protein 1; CL-K1; Colec11

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.