protein

BCAM Protein, Cynomolgus (HEK293, His)

HY-P700662

20 μg;50 μg;100 μg

145;280;450 USD

BCAM Protein, Cynomolgus (HEK293, His)

proteins

HEK293

20 μg;50 μg;100 μg

145;280;450 USD

BCAM protein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein laminin. BCAM inhibits proliferation, migration, and invasion of trophoblast cells by inhibiting PIK3R6/p-STAT3 signaling, which may lead to placental dysplasia, resulting in a preeclampsia-like phenotype. BCAM also promotes ovarian cancer metastasis. BCAM Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived BCAM protein, expressed by HEK293 , with C-His labeled tag. The total length of BCAM Protein, Cynomolgus (HEK293, His) is 517 a.a., with molecular weight of 70-80 kDa.

Cynomolgus

BCAM protein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein laminin. BCAM may play a role in red blood cell vessel occlusion in epithelial cell carcinoma and sickle cell disease. BCAM has been shown to interact with laminin α5. BCAM also promotes ovarian cancer metastasis. BCAM inhibits proliferation, migration, and invasion of trophoblast cells by inhibiting PIK3R6/p-STAT3 signaling, which may lead to placental-dysplasia, resulting in a preeclampsia-like a phenotype [1] [2] [3] [4] .

LU; MSK19; Gplu; CD239; Lutheran;

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.