protein

AOC3 Protein, Human (HEK293, His)

HY-P70065

10 μg;50 μg

190;530 USD

AOC3 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

190;530 USD

As a cell adhesion molecule, AOC3 protein plays a key role in lymphocyte extravasation and recycling by promoting the binding of lymphocytes to peripheral lymph node vascular endothelial cells, independent of L-selectin. In addition to its role in cell adhesion, AOC3 exhibits semicarbazide-sensitive monoamine oxidase activity, contributing to its enzymatic function. AOC3 Protein, Human (HEK293, His) is the recombinant human-derived AOC3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of AOC3 Protein, Human (HEK293, His) is 736 a.a., with molecular weight of ~95 kDa.

Human

AOC3, or amine oxidase, copper-containing 3, functions as a cell adhesion protein crucial for lymphocyte extravasation and recirculation. It facilitates the binding of lymphocytes to peripheral lymph node vascular endothelial cells in a manner independent of L-selectin. Additionally, AOC3 exhibits semicarbazide-sensitive monoamine oxidase (SSAO) activity, suggesting its involvement in the oxidative deamination of primary amines. Beyond its role in immune cell interactions, AOC3 may also play a part in adipogenesis, contributing to the complex processes underlying the formation and development of adipose tissue.

rHuMembrane primary amine oxidase/AOC3, His; Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1; AOC3; VAP1

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 500 mM NaCl, pH 8.0.

Shipping with dry ice.