protein

HGF Protein, Human (HEK293)

HY-P700604

2 μg;10 μg;50 μg;100 μg

30;80;225;360 USD

HGF Protein, Human (HEK293)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

30;80;225;360 USD

HGF Protein is a hepatocyte growth factor involved in signaling pathways including MET and MAPK.The HGF Protein consists of an alpha chain containing an n-terminal domain four kringle domains, and a β serine protease domain.HGF Protein, Human (HEK293) is the recombinant Virus-derived HGF protein, expressed by HEK293 , with tag free.

Human

Hepatocyte growth factor (HGF) is a potent mitogen of liver cells that acts as a growth factor for a wide range of tissue and cell types. HGF is an activating ligand of Met receptor tyrosine kinase, whose activity is essential for normal cell development and organ regeneration, but abnormal activation of Met is associated with the growth, invasion, and metastasis of many types of solid tumors. HGF activates MAPK signals after TMPRSS13 cutting and activation. HGF is a double-stranded protein consisting of 728 amino acids, the α chain contains an n-terminal domain and four kringle domains, and the β chain contains a serine protease domain. HGF, a member of the plasminogen related growth factor family, is secreted as an inactive single-chain precursor that is proteolytic to form biologically active disulfide-linked α/β heterodimers [1] [2] [3] [4] .

Hepatocyte growth factor; HPTA; HGF; SF; Scatter factor; Hepatopoietin-A

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.