protein

ANGPT1/Angiopoietin-1, Rat (P. pastoris, His)

HY-P700560

20 μg;50 μg

185;350 USD

ANGPT1/Angiopoietin-1, Rat (P. pastoris, His)

proteins

P. pastoris

20 μg;50 μg

185;350 USD

In rats, ANGPT1 (Angiopoietin-1) activates the TIE2 receptor, inducing tyrosine phosphorylation and influencing endothelial developmental processes distinct from VEGF. ANGPT1 plays a crucial role in mediating reciprocal interactions between endothelium, matrix, and mesenchyme. It participates in blood vessel maturation, emphasizing its significance in vascular development, with a potential role in early heart development. ANGPT1/Angiopoietin-1, Rat (P. pastoris, His) is the recombinant rat-derived ANGPT1/Angiopoietin-1, Rat, expressed by P. pastoris , with N-6*His labeled tag. The total length of ANGPT1/Angiopoietin-1, Rat (P. pastoris, His) is 478 a.a., with molecular weight of 57.4 kDa.

Rat

ANGPT1, also known as Angiopoietin-1 in rats, functions by binding to and activating the TIE2 receptor, inducing its tyrosine phosphorylation. This protein is implicated in endothelial developmental processes, distinct from the action of VEGF, and appears to play a crucial role in mediating reciprocal interactions between the endothelium and the surrounding matrix and mesenchyme. Additionally, ANGPT1 is involved in mediating blood vessel maturation and stability, suggesting its significance in vascular development. Notably, it may play an important role in the early development of the heart.

angiopoietin 1; angiopoietin-1; Ang1; KIAA0003; ANG-1; AGP1; AGPT; ANG1;

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.