protein

CFHR1 Protein, Human (HEK293, His)

HY-P70055

5 μg;10 μg;50 μg;100 μg

62;100;250;400 USD

CFHR1 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

62;100;250;400 USD

CFHR1, a key complement regulator, actively engages in the finely tuned complement system. Dimerized CFHR1 demonstrates avidity for tissue-bound complement fragments, challenging CFH. It also associates with lipoproteins, suggesting involvement in lipid metabolism. With a unique head-to-tail homodimeric structure, CFHR1 forms heterodimers with CFHR2 or CFHR5, showcasing its versatile role in complement-related processes. CFHR1 Protein, Human (HEK293, His) is the recombinant human-derived CFHR1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CFHR1 Protein, Human (HEK293, His) is 312 a.a., with molecular weight of 38-50 kDa.

Human

CFHR1 emerges as a pivotal figure in the intricate realm of complement regulation, showcasing its active involvement in this finely tuned system. In its dimerized forms, CFHR1 exhibits a remarkable avidity for tissue-bound complement fragments, effectively challenging the physiological complement inhibitor CFH. Beyond its regulatory prowess, CFHR1 displays an affinity for association with lipoproteins, hinting at a potential role in lipid metabolism. The unique structural arrangement of CFHR1 includes a head-to-tail homodimeric configuration, and it further forms heterodimers with CFHR2 or CFHR5, emphasizing its versatile engagement in the multifaceted orchestration of complement-related processes.

rHuComplement Factor H-related 1/CFHR1, His; Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM EDTA, pH 7.4 or 20mM PB, 8% Trehalose, 4% Mannitol, 50mM NaCl, 0.05% Tween 80, pH 7.5 or PBS, pH 8.0, 2 mM EDTA.

Room temperature in continental US; may vary elsewhere.