protein

GM-CSF Protein, Bovine (P. pastoris, His-Myc)

HY-P700512

20 μg;50 μg

295;560 USD

GM-CSF Protein, Bovine (P. pastoris, His-Myc)

proteins

P. pastoris

20 μg;50 μg

295;560 USD

The GM-CSF protein is a key cytokine that fundamentally stimulates the growth and differentiation of hematopoietic precursor cells, including granulocytes, macrophages, eosinophils, and erythrocytes. As a monomer, GM-CSF interacts with the GM-CSF receptor complex to form a dodecamer, which contains two α, two β, and two head-to-head hexamers of the ligand subunits. GM-CSF Protein, Bovine (P. pastoris, His-Myc) is the recombinant bovine-derived GM-CSF protein, expressed by P. pastoris , with C-Myc, C-6*His labeled tag. The total length of GM-CSF Protein, Bovine (P. pastoris, His-Myc) is 126 a.a., with molecular weight of 18 kDa.

Bovine

The GM-CSF Protein, a pivotal cytokine, plays a fundamental role in stimulating the growth and differentiation of hematopoietic precursor cells from diverse lineages, encompassing granulocytes, macrophages, eosinophils, and erythrocytes. Existing as a monomer, GM-CSF exerts its biological effects through the GM-CSF receptor complex, which forms a dodecamer comprising two head-to-head hexamers of two alpha, two beta, and two ligand subunits. This intricate receptor complex underscores the multi-faceted nature of GM-CSF in orchestrating cellular responses critical for hematopoiesis and immune function.

colony stimulating factor 2 (granulocyte-macrophage); GMCSF; MGC131935; MGC138897; granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; sargramostim; colony-stimulating factor; granulocyte-macrophage colony stimulating factor

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.