protein

DSG3 Protein, Human (Sf9, His)

HY-P700469

20 μg;50 μg

185;350 USD

DSG3 Protein, Human (Sf9, His)

proteins

Sf9 insect cells

20 μg;50 μg

185;350 USD

DSG3 is a component of intercellular desmosome junctions and plays a key role in promoting intercellular adhesion by participating in important interactions with plaque proteins and intermediate filaments. Carefully orchestrated interactions between DSG3 and these structural elements are critical for maintaining the integrity and strength of cell-to-cell connections. DSG3 Protein, Human (Sf9, His) is the recombinant human-derived DSG3 protein, expressed by Sf9 insect cells , with C-6*His labeled tag.

Human

Desmoglein-3 (DSG3) is an integral component of intercellular desmosome junctions, playing a crucial role in mediating cell-cell adhesion. Functioning within these junctions, DSG3 is involved in the interaction between plaque proteins and intermediate filaments, contributing to the structural integrity and stability of tissues. Notably, DSG3 interacts with Plakophilin-2 (PKP2), emphasizing its role in coordinating the assembly and maintenance of desmosomal complexes. This interaction further highlights the intricate molecular network involved in cell-cell adhesion and reinforces the importance of DSG3 in ensuring the proper function and structural cohesion of tissues through its engagement in desmosomal signaling pathways. (

PVA; CDHF6; desmoglein 3; desmoglein-3; cadherin family member 6; pemphigus vulgaris antigen; 130-kD pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0

Room temperature in continental US; may vary elsewhere.