protein

Endothelin-1/EDN1 Protein, Human (GST)

HY-P700460

20 μg;50 μg;100 μg;200 μg;250 μg;500 μg;1 mg

150;330;530;850;980;1368;1900 USD

Endothelin-1/EDN1 Protein, Human (GST)

Protein

E. coli

20 μg;50 μg;100 μg;200 μg;250 μg;500 μg;1 mg

150;330;530;850;980;1368;1900 USD

Endothelin-1/EDN1, an endothelium-derived vasoconstrictor peptide, acts as a likely ligand for G-protein coupled receptors EDNRA and EDNRB. Its binding initiates a signaling cascade in glomerular mesangial cells involving PTK2B, BCAR1, BCAR3, and GTPases RAP1 and RHOA. Furthermore, Endothelin-1/EDN1 shows binding affinity for the DEAR/FBXW7-AS1 receptor, underscoring its involvement in diverse cellular signaling and vascular regulation. Endothelin-1/EDN1 Protein, Human (GST) is the recombinant human-derived Endothelin-1/EDN1 protein, expressed by E. coli , with N-GST labeled tag.