protein

Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi)

HY-P700413

20 μg;50 μg;100 μg

320;600;950 USD

Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi)

proteins

HEK293

20 μg;50 μg;100 μg

320;600;950 USD

Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-Avi, C-mFc labeled tag.

Human

Growth Hormone R (GHR) functions as the receptor for pituitary gland growth hormone, playing a pivotal role in the regulation of postnatal body growth. Upon binding to its ligand, GHR activates the JAK2/STAT5 pathway, facilitating the intracellular signaling cascade. Additionally, the soluble form of the receptor, known as GHBP (Growth Hormone Binding Protein), serves as a reservoir for growth hormone in the bloodstream. GHBP may also exert modulatory or inhibitory effects on growth hormone signaling, contributing to the intricate regulation of growth processes.

Somatotropin receptor Serum-binding protein;

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.