protein

CCL11 Protein, Rhesus macaque (N-His)

HY-P700285

2 μg;10 μg;50 μg;100 μg

54;152;424;720 USD

CCL11 Protein, Rhesus macaque (N-His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

54;152;424;720 USD

The CCL11 protein directly promotes eosinophil accumulation in response to allergens, a key feature of allergic inflammation, without significantly affecting lymphocytes, macrophages, or neutrophils. This selective recruitment highlights the specificity of CCL11 in the coordination of immune responses, particularly in allergy. CCL11 Protein, Rhesus macaque (N-His) is the recombinant Rhesus Macaque-derived CCL11 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CCL11 Protein, Rhesus macaque (N-His) is 74 a.a., with molecular weight of ~11 kDa.

Rhesus Macaque

In response to the presence of allergens, the CCL11 protein plays a direct role in promoting the accumulation of eosinophils, which is a prominent characteristic of allergic inflammatory reactions, while showing no significant effect on lymphocytes, macrophages, or neutrophils. This selective recruitment underscores CCL11's specificity in orchestrating immune responses, particularly in the context of allergic reactions. The protein achieves this effect by binding to CCR3, emphasizing its engagement with specific receptors to regulate the migration and activation of eosinophils in response to allergenic stimuli.

CCL11; SCYA11Eotaxin; C-C motif chemokine 11; Small-inducible cytokine A11

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

Room temperature in continental US; may vary elsewhere.