protein

MCP-5/CCL12 Protein, Mouse (P. pastoris, His)

HY-P700266

20 μg;100 μg

240;672 USD

MCP-5/CCL12 Protein, Mouse (P. pastoris, His)

proteins

P. pastoris

20 μg;100 μg

240;672 USD

MCP-5/CCL12 protein promotes CCR2 chemokine receptor binding and contributes to physiological processes such as angiogenesis, inflammation, and monocyte chemotaxis.It is located extracellularly and is widely expressed in tissues such as the central nervous system.MCP-5/CCL12 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived MCP-5/CCL12 protein, expressed by P.pastoris , with C-His labeled tag.

Mouse

MCP-5/CCL12 protein serves a pivotal role by enabling CCR2 chemokine receptor binding activity, thus contributing to various physiological processes. It plays a significant part in angiogenesis, inflammatory responses, and the chemotaxis of monocytes. Predicted to be located in the extracellular region and active in the extracellular space, this protein exhibits a broad expression pattern in tissues such as the central nervous system and retina. The human ortholog(s) of this gene are implicated in several diseases, including Henoch-Schoenlein purpura, aggressive periodontitis, autoimmune diseases, gastrointestinal system cancers, and tuberculosis, underlining its potential involvement in diverse pathological conditions. The orthologous relationship with human CCL2 and CCL8 emphasizes the evolutionary conservation and functional relevance of this chemokine protein across species.

rMuMCP-5/CCL12; C-C motif chemokine 12; MCP5; SCYA12

Greater than 90 % as determined by SDS-PAGE.

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.