protein

DHH Protein, Human (His-GST, Myc)

HY-P700253

5 μg;10 μg;20 μg;50 μg;100 μg

50;87;148;275;415 USD

DHH Protein, Human (His-GST, Myc)

proteins

E. coli

5 μg;10 μg;20 μg;50 μg;100 μg

50;87;148;275;415 USD

DHH Protein, Human (His-GST, Myc) is a single non-glycosylated polypeptide chain. Desert hedgehog protein (DHH) is a member of the Hedgehog family which encodes signaling molecules that play an important role in regulating morphogenesis.

Human

Desert hedgehog (DHH) belongs to the hedgehog gene family that act as secreted intercellular signal transducers. DHH is an essential morphogen for normal testicular development and function in both mice and humans but is not present in the avian lineage. Like other hedgehog proteins, DHH signals through the patched (PTCH) receptors 1 and 2. The receptors PTCH1 and PTCH2 are highly conserved mediators of hedgehog signalling in both the developing and adult marsupial gonads. Together these findings indicate DHH is an essential therian mammal-specific morphogen in gonadal development and gametogenesis [1] .

rHuDHH; DHH; HHG-3;

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm sterile filtered 10 mM Tris-HCl, 1 mM EDTA, 6%Trehalose, pH 8.0

Room temperature in continental US; may vary elsewhere.