protein

CRHBP Protein, Human (HEK293, His)

HY-P70013

10 μg;50 μg

107;300 USD

CRHBP Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

107;300 USD

CRHBP Protein critically regulates by binding to and inactivating corticotropin-releasing factor (CRF), suggesting a role in preventing excessive pituitary-adrenal stimulation, especially during pregnancy. This interaction contributes to balancing neuroendocrine signaling pathways, ensuring appropriate physiological responses and safeguarding against pituitary-adrenal axis overstimulation, particularly in the context of pregnancy. CRHBP Protein, Human (HEK293, His) is the recombinant human-derived CRHBP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRHBP Protein, Human (HEK293, His) is 298 a.a., with molecular weight of ~40.0 kDa.

Human

The CRHBP Protein plays a crucial role by binding to corticotropin-releasing factor (CRF) and effectively inactivating it. This action suggests a regulatory function, potentially serving to prevent inappropriate pituitary-adrenal stimulation, particularly during pregnancy. By binding and inactivating CRF, CRHBP may contribute to maintaining a balance in the neuroendocrine signaling pathways, ensuring appropriate physiological responses and protecting against overstimulation of the pituitary-adrenal axis, particularly in the context of pregnancy.

rHuCorticotropin-releasing factor-binding protein/CRHBP, His ; Corticotropin-Releasing Factor-Binding Protein; CRF-BP; CRF-Binding Protein; Corticotropin-Releasing Hormone-Binding Protein; CRH-BP; CRHBP; CRFBP

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

Room temperature in continental US; may vary elsewhere.