protein

Animal-Free IL-34 Protein, Human (His)

HY-P700125AF

2 μg;10 μg;50 μg

65;170;450 USD

Animal-Free IL-34 Protein, Human (His)

proteins

E. coli

2 μg;10 μg;50 μg

65;170;450 USD

IL-34 protein is an important cytokine that promotes proliferation, survival, and differentiation of monocytes and macrophages. It plays a key role in innate immunity and inflammation by promoting the release of pro-inflammatory chemokines. Animal-Free IL-34 Protein, Human (His) is the recombinant human-derived animal-FreeIL-34 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

Human

The IL-34 Protein serves as a crucial cytokine, fostering the proliferation, survival, and differentiation of monocytes and macrophages. Its role extends to promoting the release of pro-inflammatory chemokines, thereby playing a pivotal part in innate immunity and inflammatory processes. Moreover, IL-34 assumes a critical role in the regulation of osteoclast proliferation and differentiation, impacting bone resorption. Through signaling via CSF1R and its downstream effectors, IL-34 stimulates the phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. Existing as a homodimer, IL-34 interacts specifically with CSF1R, further contributing to its intricate regulatory network.

IL34; C16orf77; IL-34; Interleukin-34; MGC34647

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 8.0, trehalose.

Room temperature in continental US; may vary elsewhere.