protein

Thymidylate Protein, Human (HEK293, His)

HY-P70012

10 μg;50 μg

152;425 USD

Thymidylate Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

152;425 USD

Thymidylate proteins play a key role in DNA synthesis by catalyzing the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP). This enzymatic process is critical for the production of dTDP, the direct precursor of the DNA building block dTTP. Thymidylate Protein, Human (HEK293, His) is the recombinant human-derived Thymidylate protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Thymidylate Protein, Human (HEK293, His) is 212 a.a., with molecular weight of ~26.0 kDa.

Human

Thymidylate kinase, an essential enzyme in nucleotide metabolism, catalyzes the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP). This phosphorylation reaction is a crucial step in the biosynthesis of deoxythymidine triphosphate (dTTP), a building block for DNA replication and repair. Thymidylate kinase utilizes ATP as the preferred phosphoryl donor, and the reaction is facilitated in the presence of Mg(2+). The enzyme's activity is integral to the maintenance of balanced nucleotide pools and the precise regulation of DNA synthesis in cells. Understanding the functions of thymidylate kinase is essential for unraveling the intricate processes involved in DNA replication and cellular proliferation.

rHuThymidylate /kinaseDTYMK, His; Thymidylate kinase; dTMP kinase; DTYMK; CDC8; TMPK; TYMK

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 20 mM PB, 5% Sucrose, 0.05% Tween 80, pH 7.4.

Shipping with dry ice.