protein

Animal-Free Intrinsic Factor/GIF Protein, Human (His)

HY-P700085AF

2 μg;10 μg;50 μg

54;150;420 USD

Animal-Free Intrinsic Factor/GIF Protein, Human (His)

proteins

E. coli

2 μg;10 μg;50 μg

54;150;420 USD

Intrinsic factor (GIF) plays a crucial role in cobalamin (Cbl) absorption in the ileum. This well-coordinated process involves the interaction of the CBLIF-cobalamin complex with the Cubilin (CUBN) receptor, leading to internalization via receptor-mediated endocytosis. Animal-Free Intrinsic Factor/GIF Protein, Human (His) is the recombinant human-derived animal-FreeIntrinsic Factor/GIF protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

Human

Intrinsic Factor (GIF) stands as a key facilitator in the absorption of the essential vitamin cobalamin (Cbl) in the ileum. Its pivotal role unfolds through a well-orchestrated process, where the CBLIF-cobalamin complex, upon interaction with the Cubilin (CUBN) receptor, undergoes internalization via receptor-mediated endocytosis. This intricate interplay underscores the significance of GIF in ensuring the effective absorption of cobalamin, a crucial vitamin for various physiological processes. GIF's interaction with CUBN, particularly involving CUB domains, highlights the molecular intricacies governing this essential aspect of vitamin uptake.

Gastric intrinsic factor; GIF; IF; Intrinsic factor; IFMH; INF; TCN3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 8.0, trehalose.

Room temperature in continental US; may vary elsewhere.