protein

Animal-Free NAP-2/CXCL7 Protein, Human (His)

HY-P700049AF

2 μg;10 μg;50 μg

79;220;440 USD

Animal-Free NAP-2/CXCL7 Protein, Human (His)

proteins

E. coli

2 μg;10 μg;50 μg

79;220;440 USD

NAP-2/CXCL7 protein (LA-PF4) triggers DNA synthesis, mitosis, glycolysis, cAMP accumulation, and hyaluronic acid synthesis. It contributes to the formation of plasminogen activator in human synovial cells and acts as a CXCR1/CXCR2 ligand together with variants such as NAP-2 (73). Animal-Free NAP-2/CXCL7 Protein, Human (His) is the recombinant human-derived animal-FreeNAP-2/CXCL7 protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free NAP-2/CXCL7 Protein, Human (His) is 70 a.a., with molecular weight of ~8.43 kDa.This product is for cell culture use only.

Human

NAP-2/CXCL7 Protein, also known as LA-PF4, exerts a range of biological activities including stimulating DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and the synthesis of hyaluronic acid and sulfated glycosaminoglycan. It plays a role in promoting the formation and secretion of plasminogen activator by human synovial cells. As a ligand for CXCR1 and CXCR2, NAP-2, along with its variants, such as NAP-2(73), NAP-2(74), NAP-2(1-66), and the potent NAP-2(1-63), acts as chemoattractants and activators for neutrophils. Antibacterial proteins TC-1 and TC-2 are released in vitro from activated platelet alpha-granules. Additionally, CTAP-III(1-81) exhibits higher potency than CTAP-III in desensitizing chemokine-induced neutrophil activation, while beta-thromboglobulin functions as a homotetramer.

NAP-2/CXCL7; C-X-C motif chemokine 7; Platelet basic protein; MDGF; SCYB7

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 7.4, trehalose.

Room temperature in continental US;may vary elsewhere.