protein

Animal-Free I-TAC/CXCL11 Protein, Human (His)

HY-P700042AF

2 μg;10 μg;50 μg

63;165;430 USD

Animal-Free I-TAC/CXCL11 Protein, Human (His)

proteins

E. coli

2 μg;10 μg;50 μg

63;165;430 USD

I-TAC/CXCL11 protein selectively attracts interleukin-activated T-cells, inducing calcium release and binding to CXCR3 receptors. It does not attract unstimulated T-cells, neutrophils, or monocytes. This protein may play a role in T-cell recruitment in central nervous system diseases and skin immune responses. It also interacts with TNFAIP6, potentially modulating inflammatory processes. Animal-Free I-TAC/CXCL11 Protein, Human (His) is the recombinant human-derived animal-FreeI-TAC/CXCL11 protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free I-TAC/CXCL11 Protein, Human (His) is 73 a.a., with molecular weight of ~9.11 kDa.This product is for cell culture use only.

Human

I-TAC/CXCL11 protein demonstrates chemotactic activity specifically for interleukin-activated T-cells while not attracting unstimulated T-cells, neutrophils, or monocytes. It induces calcium release specifically in activated T-cells and binds to CXCR3 receptors. This protein may have a significant role in central nervous system diseases that involve T-cell recruitment, as well as in skin immune responses. Additionally, it interacts with TNFAIP6 through its Link domain, suggesting potential involvement in modulating inflammatory processes.

I-TAC/CXCL11; C-X-C motif chemokine 11; Beta-R1; H174; IP-9; SCYB11

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 7.4, trehalose.

Room temperature in continental US; may vary elsewhere.