protein

Animal-Free CDNF Protein, Human (His)

HY-P700038AF

2 μg;10 μg;50 μg

45;120;335 USD

Animal-Free CDNF Protein, Human (His)

proteins

E. coli

2 μg;10 μg;50 μg

45;120;335 USD

CDNF (cerebral dopamine neurotrophic factor) functions as an important trophic factor, providing unique support to dopamine neurons. Its protective effect has a clear role in preventing 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. Animal-Free CDNF Protein, Human (His) is the recombinant human-derived animal-FreeCDNF protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

Human

CDNF (Cerebral Dopamine Neurotrophic Factor) emerges as a vital trophic factor with a distinctive role in supporting dopamine neurons. Its protective capabilities extend to preventing the degeneration of dopaminergic neurons induced by 6-hydroxydopamine (6-OHDA). Notably, when administered subsequent to 6-OHDA-lesioning, CDNF exhibits the remarkable ability to restore dopaminergic function and effectively thwart the degeneration of neurons within the substantia nigra, underscoring its therapeutic potential in mitigating neurodegenerative processes.

Cerebral dopamine neurotrophic factor; ARMET-like protein 1; Conserved dopamine neurotrophic factor; ARMETL1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 8.0, trehalose.

Room temperature in continental US; may vary elsewhere.