protein

DPEP1 Protein, Human (HEK293, His)

HY-P70003

10 μg;50 μg

107;300 USD

DPEP1 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

107;300 USD

Dipeptidase 1 (DPEP1) has multiple enzymatic functions and can hydrolyze various dipeptides, including the conversion of leukotriene D4 to leukotriene E4. It is also involved in the degradation of cysteinylbisglycine resulting from the breakdown of glutathione. DPEP1 Protein, Human (HEK293, His) is the recombinant human-derived DPEP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DPEP1 Protein, Human (HEK293, His) is 369 a.a., with molecular weight of ~41.0 kDa.

Human

Dipeptidase 1 (DPEP1) exhibits versatile enzymatic functions, hydrolyzing a broad spectrum of dipeptides, including the conversion of leukotriene D4 to leukotriene E4. Additionally, it plays a role in the degradation of cystinyl-bis-glycine formed during glutathione breakdown. Notably, DPEP1 showcases beta lactamase activity, enabling the hydrolysis of the beta-lactam antibiotic imipenem. Beyond its enzymatic functions, DPEP1 acts as an adhesion receptor, facilitating neutrophil recruitment from the bloodstream into inflamed lungs and liver independently of its dipeptidase activity.

rHuDipeptidase 1/DPEP1, His; Dipeptidase 1; Dehydropeptidase-I; Microsomal Dipeptidase; Renal Dipeptidase; hRDP; DPEP1; MDP; RDP

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Shipping with dry ice